Psychiatric Medication Discontinuation/Reduction Study (PMDR)

The Psychiatric Medication Discontinuation/Reduction study (PMDR) is the first U.S. survey of a large sample of longer-term users who chose to discontinue psychiatric medications. The study, funded by the Foundation for Excellence in Mental Health Care and led by current and former users of psychiatric medications, sought to understand first-hand experiences and strategies of individuals who decided to discontinue psychiatric medications, and either stopped or reduced the use of these medications.

The experience of discontinuation itself was reported to be physically and emotionally challenging, with respondents reporting several  undesirable withdrawal effects that have been noted in previous research. Nonetheless, 82% of respondents who achieved their medication goals reported being satisfied or very satisfied with their decision.